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BMAC® (Bone Marrow Aspirate Concentrate) System
The BMAC system is used to concentrate bone marrow aspirate (BMA) derived from a patient’s own bone marrow.... More Info Less Info




The concentrated BMA produced using the BMAC System contains a rich mixture of components, including stem cells, progenitor cells, platelets, growth factors, lymphocytes and granulocytes.1,2,3 The BMAC process disposable includes a proprietary, self-calibrating floating shelf that is designed for concentrating BMA with consistently high recovery rates. The density of the floating shelf is engineered to maximize the capture of the TNCs in bone marrow. 
1 Hermann PC, Huber SL, Herrier T, et al. Concentration of bone marrow total nucleated cells by a point-of-care device provides a high yield and preserves their functional activity. Cell Transplant. 2008;16(10):1059-1069.
2 Gianakos A, Sun L, Patel J, Adams D, Liporace F. Clinical application of concentrated bone marrow aspirate in orthopaedics: A systematic review. World J Orthop. 2017;8(6):491.
3 Hansraj KK. Stem cells in spine surgery. Surg Technol Int . 2016;10(29):348-358.

PRP®
Platelet-rich plasma (PRP) is plasma that contains a higher concentration of platelets than is typical for whole blood.... More Info Less Info




While platelet concentration is the primary focus of autologous PRP, preparations also contain growth factors that may help optimize the conditions needed for healing.1,2,3 Other cellular components of PRP include white blood cells and peripheral stem cells. These components all play a biological role in the healing process and are provided at concentrated levels using the platelet concentrate system.
1 Giusti I, Rughetti A, D’Ascenzo S, et al. Identification of an optimal concentration of platelet gel for promoting angiogenesis in human endothelial cells. Transfusion.
2009;49(4):771-778.
2 El-Sharkawy H, Kantarci A, Deady J, et al. Platelet-rich plasma: growth factors and pro- and anti-inflammatory properties. J Periodontol. 2007;78(4):661-669.
3 Fiore S, Serhan C. Lipoxin A4 receptor activation is distinct from that of the formyl peptide receptor in myeloid cells: inhibition of CD11/18 expression by lipoxin A4-lipoxin A4 receptor interaction. Biochemistry. 1995;34(51):16678-16686.

AdiPrep® Adipose Concentration System
Concentrated adipose tissue provides clinicians with a stem-cell-rich product in the form of a 3D scaffold with a high concentration of MSCs.... More Info Less Info




Adipose tissue is a heterogeneous biological tissue that offers stem cell content and cellular heterogeneity in a concentration that is higher than that of PRP but lower than that of concentrated BMA.1 The AdiPrep system can generate an adipose graft capable of delivering a high concentration of stem cells directly to the application site.2
1 Bourin P, Bunnell BA, Casteilla L, et al. Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the International Federation for Adipose Therapeutics and Science (IFATS) and the International Society for Cellular Therapy (ISCT). Cytotherapy. 2013;15(6):641-648.
2 Internal data. Data on file.

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